Sr. Manager, CMC Sourcing and Supplier Management

Office Location: Verona, WI

Arrowhead Pharmaceuticals, Inc. (Nasdaq:  ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA.  Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. 

The Position

Manage and drive activities for sourcing / contract management and supplier management, including identifying and developing GMP material suppliers and service providers. Oversee all GMP related sourcing and procurement activities.


Supplier management:

  • Manage suppliers in collaboration with internal stakeholders, including business requirements, sourcing and risk management strategy, supplier selection and qualification, contracting, and performance management
  • Collaborate with inventory/planning team to develop effective supply plan and ensure risk management plan is in place and kept up to date for critical supply
  • Work closely with the Quality on audit, investigation, complaints, change control and GMP systems monitoring, and follow through with action plan implementation
  • Facilitate supplier risk management program in partnership with internal stakeholders – identification, assessment, mitigation planning and execution including metrics to report on supplier health status and escalating business risks as needed
  • Maintain E2E supply chain maps for all products and key sub-supply chains

Sourcing / contract management:

  • Review and select appropriate suppliers and materials based on business requirements
  • Oversee procurement activities for all GMP materials and services
  • Negotiate, implement, and manage agreements while achieving commercial savings
  • Ensure timely establishment and administration of supply and quality agreements


  • Bachelor’s degree in a related field
  • 5 or more years of purchasing experience
  • Experience working within D365
  • Experience working with external vendors
  • Excellent negotiating and leadership skills
  • Effective collaboration skills when working interdepartmental and external
  • High attention to detail


Wisconsin pay range
$120,000$150,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.   

All applicants must have authorization to work in the US for a company.   

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