Research Technician, Toxicology and Pathology


Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, our therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specified gene, thereby affecting the production of a specific protein. Our RNAi-based therapeutics are at the leading edge with the potential to bring life changing treatments for patients.

Our Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. The TRiM platform builds on more than a decade of work on targeted RNA delivery and offers several advantages including simplified manufacturing and reduced costs; multiple routes of administration; and potential for improved safety.

Our employees are nimble, science-driven, innovative professionals. A career at Arrowhead offers the opportunity to collaborate with top notch scientists to rapidly discover and develop RNAi-based therapeutics in a variety of indications to add to our growing pipeline. Research and development activities are located in Madison, WI. Our R&D group includes fully-integrated capabilities for chemistry, biology, toxicology and manufacturing.

Madison is an exciting and sophisticated city that includes state government, the flagship campus of the University of Wisconsin, and major research organizations.

The Position

Arrowhead Pharmaceuticals, Inc. seeks a full time Research Technician to join its Toxicology/Pathology team at its research and development facility in Madison, WI. The ideal candidate should be highly motivated, enjoy working in a fast-paced environment, have some experience with basic histology techniques and have the desire to learn new laboratory methods. Day to day activities would include performing cryosectioning of animal tissues, routine automated tissue processing, paraffin embedding and microtome sectioning, and performing immunohistochemical and/or immunofluorescence staining.

Secondary responsibilities include cell culture, running ELISA and other multiwell plate assays, and working with the animal research facility to aid in tissue harvesting.


  • Bachelor’s in Cell Biology, Molecular Biology, Biochemistry or a related discipline
  • Minimum of one year of experience in a histology lab or research lab environment
  • Highly detailed oriented individual with the ability to follow procedures and multitask.
  • Strong communication and documentation skills.
  • Proficient with Microsoft based programs


  • Experience with methods and technologies involving tissue processing and sectioning, various types of staining, and light and fluorescence microscopy.
  • Certification as a Histological Technician/Technologist with the American Society for Clinical Pathology (HT/HTL ASC) is desired but not necessary.

Please submit a resume and cover letter to

Arrowhead provides competitive salaries and an excellent benefit package.

All applicants must have authorization to work in the U.S. for a company.