Overview
Arrowhead Pharmaceuticals develops innovative RNAi-based therapeutics to treat diseases by silencing causative genes. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Pipeline Development Strategy
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, characterized by the overproduction of one or more proteins. The depth and versatility of our RNAi technologies enable us to address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise druggable by small molecules and biologics.
Leadership
Arrowhead has built an experienced team of leaders that foster a culture of innovation and have a proven ability to advance development programs from idea stage into commercial pharmaceutical products.
Executive Leadership
Department Heads
Vincent Anzalone, CFA
Vice President, Head of Investor Relations
Dave Bormett, MS
Vice President, Quality Assurance
Erik Bush, Ph.D.
Group Vice President, Biology
Peter Carignan, MA, MBA
Vice President, Clinical Operations
Zhi-Ming Ding, M.D., Ph.D.
Vice President, Biology
Christine Esau, Ph.D.
Vice President, Biology
Fred Fleitz, Ph.D.
Group Vice President, Chemistry, Manufacturing & Controls
Leslie Lemke-Boutcher
Vice President, Nonclinical Toxicology
Nadia Meshkova, MBA
Vice President, Treasurer
Tao Pei, Ph.D.
Group Vice President, Chemistry
Matt Pulisic, MBA
Vice President of Finance
Thomas Schluep, Sc.D.
Vice President, Program Management
Jack Shi, Ph.D.
Vice President, Clinical Pharmacology
Randy Steiner, DPA, MS
Vice President, Regulatory Affairs
Aaron Tan, MBT
Head of Tax