Annual Statement of Compliance

Arrowhead Pharmaceuticals, Inc.  (“Arrowhead”) declares that to the best of its knowledge, information, and belief, it is in compliance with its Comprehensive Compliance Program, which complies with its good faith understanding of the requirements of California Health and Safety Code 119400-119402.  For any questions regarding Arrowhead’s Compliance program, please contact Arrowhead Compliance at 1-866-80ARROW.

Dated: November 18, 2025