Biology

Assistant I, In Vivo Research

Office Location: San Diego, California, United States

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI.  Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. 

The Position

The Assistant, In Vivo Research will perform basic study support activities, as well as clerical and administrative duties to support In Vivo Pharmacology projects and research.

This role is onsite 5 days a week in San Diego.

Responsibilities

  • Label tubes, cassettes, and other materials for functions based on study files
  • Assist in the preparation and review of files for In Vivo studies
  • Use Excel to record tube and material information into study files
  • Proactively monitor inventory levels and order stock in preparation or as requested
  • Identify new and/or replacement products as requested
  • Prepare buffer solutions, fixatives, and/or dosing solutions
  • Complete general laboratory cleaning, organization, and/or general lab maintenance
  • Communicate with study leads, teammates, or other cross-functions as needed to problem solve study needs
  • May train other Assistants and peers
  • May provide support to various areas within the In Vivo Pharmacology team
    • Assist with cage wash, filling cages, cage cleaning, or similar duties
    • Sort and weigh samples/tubes
    • Assist with body weights, and/or preparation for dosing/surgery
    • Centrifuging and aliquoting blood samples
    • Prepare dosing syringes
    • Update animal information based on study design and make cage cards

Requirements

  • Proficiency with Microsoft Suite programs (i.e. Excel, Word) 
  • Strong organizational skills 
  • Ability to prioritize tasks  
  • Strong attention to detail 
  • Ability to communicate to all levels of the organization 
  • Ability to adapt to changes in priority and/or studies
  • Ability to work in fast paced environment
  • Knowledge of In Vivo procedures and practices

Preferred

  • Associate's Degree & some relevant experience (or High School Diploma & 3+ years of experience in a laboratory setting)
  • Background in animal husbandry, restraint and handling 
  • Must demonstrate a commitment to quality care of laboratory animals 
California pay range
$50,000$55,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.   

Candidates must have current, valid authorization to work in the country where this role is located.

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