Director, Patient Advocacy, Cardiometabolic Franchise

Office Location: Pasadena, CA or San Diego, CA

Arrowhead Pharmaceuticals, Inc. (Nasdaq:  ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA.  Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. 

The Position

Let’s do something amazing together!  The Director Patient Advocacy, Cardiometabolic Franchise, will play a pivotal role in the launches of Arrowhead’s leading investigational cardiometabolic medicines – Plozasiran (siRNA targeting APOC3) and Zodasiran (siRNA targeting ANGPTL3).  These molecules have demonstrated compelling clinical data to date and are in late-stage development for the treatment of various grievous conditions.  You will play an integral role in developing patient engagement/advocacy strategies, building and maintaining strong relationships with key stakeholders, and ensuring patient centricity is at the heart of everything we do.  Patients are counting on us to deliver with speed and excellence.  Do you have what it takes to make a major difference in their lives?


  • Design and develop patient engagement/advocacy strategies and initiatives
  • Identify, prioritize, and collaborate with relevant patient organizations, associations, and networks
  • Establish and maintain strong working relationships with key internal and external stakeholders
  • Represent Arrowhead at external events and meetings with relevant patient groups and advocates
  • Coordinate and support patient engagement activities, such as advisory boards, focus groups, surveys, influencer initiatives, patient testimonials, and educational programs
  • Contribute to cross-functional Launch Team(s) by representing the patient voice and ensuring the team’s understanding of critical patient insights and needs; ensure the patient voice is integrated into Arrowhead’s clinical development and early commercialization plans
  • Monitor and report on patient advocacy trends, best practices, and opportunities
  • Participate in various ad hoc projects where the patient is at the center, including participating in the development of patient-focused marketing materials and patient support programs
  • Manage relevant patient advocacy budget and resources


  • Master’s degree and 5+ years of patient advocacy or public affairs experience in the biopharmaceutical industry OR Bachelor’s degree and 7+ years of patient advocacy or public affairs experience in the biopharmaceutical industry
  • Willingness and ability to travel as needed domestically and internationally to support the strategy.


  • Previous experience in patient advocacy or public affairs roles in the biopharmaceutical industry or at a patient organization
  • Solid understanding of foundational advocacy competencies
  • Track record of successful execution of patient centricity/advocacy initiatives
  • Ability to work productively in a matrixed, team-based environment, managing projects involving multiple functions and shared accountabilities
  • Excellent communication, presentation, and interpersonal skills
  • Demonstrated strength in insight generation and ability to translate these insights into action
  • Strong organizational and time management skills
  • Experience in cardiometabolic therapeutic area, preferably with a focus on dyslipidemias and a deep understanding of the patient journey, unmet needs, and challenges/opportunities
  • A strong network and established relationships with patient groups and advocates in the cardiometabolic therapeutic area
  • A passion for improving the lives of patients and their families
California pay range
$215,000$235,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.   

All applicants must have authorization to work in the US for a company.   

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