Plant Operations
Manager, Manufacturing (3rd Shift)
Office Location: Verona, WI
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The Manufacturing Manager will work in the Plant Operations Group. They will supervise, train, and develop a team of Production Chemists/Technicians and be responsible for delivering non-GMP and GMP batches of drug substance for clinical, commercial, and toxicology needs.
This is a 3rd shift position, working four 10-hour shifts Monday – Thursday. This role is eligible for a 15% shift differential.
Responsibilities
- Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentations at team meetings
- Organize and lead a team of scientists in the implementation of new processes in a GMP environment
- Recruit, train, and mentor team members
- Oversee/guide writing of SOPs, WIs, and batch records
- Provide technical oversight during production, and suggest solutions for issues as they occur
- Collaborate with planning and program management to ensure schedule adherence
- Assist with manufacturing and other duties as necessary
Requirements:
- BS or MS in chemistry, biochemistry, or engineering field
- 5 years’ experience in a GMP/GLP laboratory settings
- Good verbal and written communication skills
- Experience with analytical techniques, especially HPLC
- Demonstrated leadership through leading direct reports or through matrix organizations
- Proficient in MS Office Suite
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.